Computational and theoretical approaches to the study of biological networks at the cellular and molecular level. Multiscale and multilevel approaches to study biomolecular processes. Assembly of macromolecular complexes on DNA, membranes, and scaffols. Statistical mechanics basis of gene regulation and signal transduction. Noise in cellular processes. In vivo biomolecular mechanics. Molecular biophysics: membranes, membrane associated proteins, and their interactions with small molecules and drugs.
Finite element methods, aerospace structures, aeroelasticity, biomechanics, and vibro-acoustics.
Michael A. Savageau
Integrated behavior of organizationally complex systems, quantitative relationship of such behavior to its underlying molecular determinants, generic methods for mathematical and computer analysis of such systems, application of such methods to specific classes of cellular and molecular networks, biological design principles governing the organization of metabolic pathways and gene circuits, system robustness.
Creative and mechanical design, dynamics, kinematic geometry, and applied differential geometry.
S. Geoffrey Schladow
Interaction between fluid transport and mixing processes with water quality in natural and engineered systems. Examples of such systems include lakes, rivers, estuaries and mining pits. Using a combination of field experimentation, detailed laboratory studies and numerical modeling, he is better quantifying the critical flux paths in these systems. The results of this work will lead to improved methods of managing and controlling our water resources.
Nanostructured and ultrafine grained materials. Green materials and green engineering design
Nanostructured materials, energy storage, high-throughput material characterization platforms, structure-property relationships in micro- and nano-scale, tissue-material and biomolecule-surface interactions, electrochemical biosensors, BioMEMS, microfluidic flow control schemes, multifunctional biomedical devices, drug delivery, neural electrodes.
Teaching Applied Biological Systems Technology (ABT) courses at Western Center for Agricultural Equipment (WCAE)
The Shah Lab uses viruses and engineering principles to perturb the autophagy network, which is responsible for recycling cellular components into primary biological building blocks. Autophagy is important for many processes, including viral infection and protein production, and dysfunction of autophagy is implicated in neurodegenerative diseases and aging. The insights we gain from studying and engineering the autophagy network will be useful to many areas of biology, medicine and biotechnology. We use complementary techniques of global proteomics, genetics, high-throughput sequencing, microscopy and synthetic biology.
Optical Characterization of Groundwater Nitrate Levels; Soret Transport Effects on Liquid Fuel Combustion; Bi-Component Droplet Combustion in Reduced Gravity; Field-Assisted Combustion Synthesis in Reduced Gravity; Combustion of HAN-Based Monopropellant Droplets in Reduced Gravity; Visualization of Flows Inside Droplets; Combustion of Rectilinear Droplet Streams With and Without Wall Influences; Computational Modeling of Droplet Dynamics; Photonic Device for Measurement of Delineations of Vehicles on the Highway; Electrothermal Ramjet; Molten Salt Destruction of Waste Energetic Materials; Asymptotic Modeling of Aerosol Dynamics, Asymptotic Modeling of Structures of Electric Arcs; Combustion of Slurry Droplets with Nano-Sized Aluminum Particles; Measurement of Droplet Composition Changes using Fiber-Optic Spectroscopy.
Eduardo A. Silva
Our research focuses on the field of translation stem cell bioengineering. Our research aim is to develop new material platforms that enable one to control stem/progenitor cell trafficking in the body.
Scott I. Simon
Biomechanics of cells and tissues, neutrophil biology, vascular engineering, particularly with respect to inflammatory disease; fluorescence flow cytometry.
Instrumentation and postharvest engineering for biological materials; packaging, handling, storage and transportation of agricultural commodities; nondestructive measurement of the quality and composition of biological materials; robotics, control and vision systems.
Manufacturing systems and processes, CNC machine tools, mechanical and mechatronics design and analysis, high performance machining, CAD/CAM/CAE, production technologies
Transportation planning and policy analysis; Environmental impact of motor vehicles.
Vivek J. Srinivasan
Biophotonics technologies for basic and translational research and clinical diagnostics , neuroimaging, neurovascular coupling, cerebral blood flow and metabolism, in vivo functional optical imaging, light-tissue interactions.
Professor Stroeve conducts fundamental work on colloid and surface science, self-assembled monolayers, Langmuir-Blodgett films, supramolecular structures on surfaces, supported lipid bilayers, transport in colloids and tissues, nanotechnology, bio-nanotechnology, lithium ion batteries, solar energy, and membrane separations.
My research interests span programming languages, software engineering, and computer security, focusing on developing methodologies, techniques and tools for improving software reliability & security and programming productivity.