All publications can be found at https://scholar.google.com/citations?user=cD0huCsAAAAJ&hl=en .

Sampling of recent publications from the Leach Lab:

  1. Hoang TTH, Griffin KH, Aragon H, Leach JK. Myogenesis and inflammatory response of fibro-adipogenic progenitors are regulated by hydrogel biophysical properties. ACS Applied Bio Materials PMID: 41395664.
  2. Hoang TTH, Filler AC, Ramos-Rodriguez DA, Leach JK. Modulating iMSC spheroid function with mechanically tunable hydrogels to strengthen the bone-muscle axis. ACS Biomaterials Science & Engineering PMID: 41392412
  3. Wheeler EE, Apsey AN, Leach JK. Zwitterionic microgel scaffolds support matrix accumulation by regulating protein adsorption. Advanced Healthcare Materials 2025; e03483. PMID: 41199679.
  4. Saiz AM, Rahmati M, Baldini TD, Bhat AS, Johnson SD, Liu M, Reyes RM, Fok SW, Lee MA, El Khassawna T, Wieland DCF, Marinho AL, Blanchet C, Leach JK, Haugen HJ. Mesenchymal stem cells delivered via a bioactive disordered peptide-hydrogel modulate early inflammation and enhance skeletal repair in a polytrauma model. Journal of Tissue Engineering 2025; 16:20417314251397106. PMID: 41340773.
  5. Griffin KH, Sagheb IS, Coonan TP, Wu LA, Rowland DJ, Arzi B, Lewis JS, Leach JK. Controlled delivery of immunomodulatory factors for mineralized tissue formation in an inflammatory microenvironment. Advanced Healthcare Materials 2025; e02466. PMID: 40878386.
  6. Saiz AS, Rahmati M, Johnson SD, Bhat AS, Baldini TD, Øvrebø Ø, Nogueira LP, El Khassawna T, Stötzel S, Fierro FA, Lee MA, Leach JK, Haugen HJ. Systemic versus local delivery of mesenchymal stem cells to improve the early stages of fracture healing in a polytrauma model. Journal of Biological Engineering 2025; 19(1):82. PMID: 41029699.
  7. Ambrosi TH, Morales D, Chen K, Weldon K, Wang Y, Murphy M, Wheeler EE, Hunt E, Saiz A, Leach JK, Fierro F, Chan CKF, Lane NE. Basigin links altered skeletal stem cell lineage dynamics with glucocorticoid-induced bone loss and impaired angiogenesis. Nature Communications 2025; 16(1):7606. PMID: 40817087.
  8. Mierswa SC†, Wheeler EE†, Apsey AN, Jeon O, Alsberg E, Leach JK. Stromal cell chondrogenic differentiation is mediated by stiffness gradient in photocrosslinkable hydrogels. Journal of Biomedical Materials Research Part A 2025; 113(5):e37928. PMID: 40349364.
  9. Jeon O, Park H, Leach JK, Alsberg E. Biofabrication of engineered tissues by 3D bioprinting of tissue specific high cell-density bioinks. Materials Today 2025; 86:172-182.
  10. Ambrosi TH, Taheri S, Chen K, Sinha R, Wang Y, Hunt EJ, Goodnough LH, Murphy MP, Steininger HM, Hoover MH, Felix FF, Weldon KC, Koepke LS, Sokol J, Liu DD, Zhao L, Conley SD, Lu W-J, Morri M, Neff NF, Van Rysselberghe NL, Wheeler EE, Wang Y, Leach JK, Saiz A, Wang A, Yang GP, Goodman S, Bishop J, Gardner M, Wan D, Weissman IL, Longaker MT, Sahoo D, Chan CKF. Human skeletal development and regeneration is shaped by skeletal stem cell diversity. Cell Stem Cell 2025; S1934-5909(25)00081-5. PMID: 40118065.