{"id":36,"date":"2020-11-25T17:58:31","date_gmt":"2020-11-25T17:58:31","guid":{"rendered":"https:\/\/faculty.engineering.ucdavis.edu\/leach-new\/?page_id=36"},"modified":"2026-01-20T18:13:00","modified_gmt":"2026-01-21T02:13:00","slug":"publications","status":"publish","type":"page","link":"https:\/\/faculty.engineering.ucdavis.edu\/leach\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"36\" class=\"elementor elementor-36\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-56e4c78c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"56e4c78c\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-c7f91e\" data-id=\"c7f91e\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7a7c64af elementor-widget elementor-widget-page-title\" data-id=\"7a7c64af\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"page-title.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\n\t\t<div class=\"hfe-page-title hfe-page-title-wrapper elementor-widget-heading\">\n\n\t\t\t\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\n\t\t\t\t\t\t\t\t\n\t\t\t\tPublications  \n\t\t\t<\/h2 > \n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-35381b2f elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"35381b2f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-60db4c00 elementor-widget elementor-widget-text-editor\" data-id=\"60db4c00\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div role=\"main\"><div><div><p>All publications can be found at https:\/\/scholar.google.com\/citations?user=cD0huCsAAAAJ&amp;hl=en .<\/p><p>Sampling of recent publications from the Leach Lab:<\/p><ol><li>Hoang TTH, Griffin KH, Aragon H, <strong><u>Leach JK<\/u><\/strong>. Myogenesis and inflammatory response of fibro-adipogenic progenitors are regulated by hydrogel biophysical properties. <em>ACS Applied Bio Materials <\/em> PMID: 41395664.<\/li><li>Hoang TTH, Filler AC, Ramos-Rodriguez DA, <strong><u>Leach JK<\/u><\/strong>. Modulating iMSC spheroid function with mechanically tunable hydrogels to strengthen the bone-muscle axis. <em>ACS Biomaterials Science &amp; Engineering<\/em> PMID: 41392412<\/li><li>Wheeler EE, Apsey AN, <strong><u>Leach JK<\/u><\/strong>. Zwitterionic microgel scaffolds support matrix accumulation by regulating protein adsorption. <em>Advanced Healthcare Materials<\/em> 2025; e03483. PMID: 41199679.<\/li><li>Saiz AM, Rahmati M, Baldini TD, Bhat AS, Johnson SD, Liu M, Reyes RM, Fok SW, Lee MA, El Khassawna T, Wieland DCF, Marinho AL, Blanchet C, <strong><u>Leach JK<\/u><\/strong>, Haugen HJ. Mesenchymal stem cells delivered via a bioactive disordered peptide-hydrogel modulate early inflammation and enhance skeletal repair in a polytrauma model. <em>Journal of Tissue Engineering<\/em> 2025; 16:20417314251397106. PMID: 41340773.<\/li><li>Griffin KH, Sagheb IS, Coonan TP, Wu LA, Rowland DJ, Arzi B, Lewis JS, <strong><u>Leach JK<\/u><\/strong>. Controlled delivery of immunomodulatory factors for mineralized tissue formation in an inflammatory microenvironment. <em>Advanced Healthcare Materials<\/em> 2025; e02466. PMID: 40878386.<\/li><li>Saiz AS, Rahmati M, Johnson SD, Bhat AS, Baldini TD, \u00d8vreb\u00f8 \u00d8, Nogueira LP, El Khassawna T, St\u00f6tzel S, Fierro FA, Lee MA, <strong><u>Leach JK<\/u><\/strong>, Haugen HJ. Systemic versus local delivery of mesenchymal stem cells to improve the early stages of fracture healing in a polytrauma model. <em>Journal of Biological Engineering<\/em> 2025; 19(1):82. PMID: 41029699.<\/li><li>Ambrosi TH, Morales D, Chen K, Weldon K, Wang Y, Murphy M, Wheeler EE, Hunt E, Saiz A, <strong><u>Leach JK<\/u><\/strong>, Fierro F, Chan CKF, Lane NE. Basigin links altered skeletal stem cell lineage dynamics with glucocorticoid-induced bone loss and impaired angiogenesis. <em>Nature Communications<\/em> 2025; 16(1):7606. PMID: 40817087.<\/li><li>Mierswa SC<sup>\u2020<\/sup>, Wheeler EE<sup>\u2020<\/sup>, Apsey AN, Jeon O, Alsberg E, <strong><u>Leach JK<\/u><\/strong>. Stromal cell chondrogenic differentiation is mediated by stiffness gradient in photocrosslinkable hydrogels. <em>Journal of Biomedical Materials Research Part A <\/em>2025; 113(5):e37928. PMID: 40349364.<\/li><li>Jeon O, Park H, <strong><u>Leach JK<\/u><\/strong>, Alsberg E. Biofabrication of engineered tissues by 3D bioprinting of tissue specific high cell-density bioinks. <em>Materials Today <\/em>2025; 86:172-182.<\/li><li>Ambrosi TH, Taheri S, Chen K, Sinha R, Wang Y, Hunt EJ, Goodnough LH, Murphy MP, Steininger HM, Hoover MH, Felix FF, Weldon KC, Koepke LS, Sokol J, Liu DD, Zhao L, Conley SD, Lu W-J, Morri M, Neff NF, Van Rysselberghe NL, Wheeler EE, Wang Y, <strong><u>Leach JK<\/u><\/strong>, Saiz A, Wang A, Yang GP, Goodman S, Bishop J, Gardner M, Wan D, Weissman IL, Longaker MT, Sahoo D, Chan CKF. Human skeletal development and regeneration is shaped by skeletal stem cell diversity. <em>Cell Stem Cell<\/em> 2025; S1934-5909(25)00081-5. PMID: 40118065.<\/li><\/ol><\/div><\/div><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Publications All publications can be found at https:\/\/scholar.google.com\/citations?user=cD0huCsAAAAJ&amp;hl=en . Sampling of recent publications from the Leach Lab: Hoang TTH, Griffin KH, Aragon H, Leach JK. Myogenesis and inflammatory response of fibro-adipogenic progenitors are regulated by hydrogel biophysical properties. ACS Applied Bio Materials PMID: 41395664. Hoang TTH, Filler AC, Ramos-Rodriguez DA, Leach JK. Modulating iMSC spheroid [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"inline_featured_image":false,"footnotes":""},"class_list":["post-36","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/faculty.engineering.ucdavis.edu\/leach\/wp-json\/wp\/v2\/pages\/36","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/faculty.engineering.ucdavis.edu\/leach\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/faculty.engineering.ucdavis.edu\/leach\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/faculty.engineering.ucdavis.edu\/leach\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/faculty.engineering.ucdavis.edu\/leach\/wp-json\/wp\/v2\/comments?post=36"}],"version-history":[{"count":43,"href":"https:\/\/faculty.engineering.ucdavis.edu\/leach\/wp-json\/wp\/v2\/pages\/36\/revisions"}],"predecessor-version":[{"id":1055,"href":"https:\/\/faculty.engineering.ucdavis.edu\/leach\/wp-json\/wp\/v2\/pages\/36\/revisions\/1055"}],"wp:attachment":[{"href":"https:\/\/faculty.engineering.ucdavis.edu\/leach\/wp-json\/wp\/v2\/media?parent=36"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}