Publications

Hwang MS, Lindenmuth BE, McDonald KA, Falk BW. “Bipartite and tripartite Cucumber mosaic virus-based vectors for producing the Acidothermus cellulolyticus endo-1,4-beta-glucanase and other proteins in non-transgenic plants.” BMC Biotechnol. Sep 21;12(1):66. (2012).
Ting-Kuo Huang and Karen A. McDonald, “Bioreactor systems for in vitro production of foreign proteins using plant cell cultures.” Biotechnol Adv. Mar-Apr;30(2):398-409. (2012).

Sang-Kyu Jung and Karen A. McDonald, “Visual Gene Developer: a fully programmable bioinformatics software for synthetic gene optimization”, BMC Bioinformatics, 12(1): 340 (2011).
Lucas Arzola, Junxing Chen, Kittipong Rattanaporn, James M. Maclean and Karen A. McDonald, “Transient Co-Expression of Post-Transcriptional Gene Silencing Suppressors for Increased in Planta Expression of a Recombinant Anthrax Receptor Fusion Protein”, Int. J. Mol. Sci, 12: 4975-4990 (2011).
Benjamin E. Lindenmuth and Karen A. McDonald, “Production and characterization of Acidothermus cellulolyticus endoglucanase in Pichia pastoris”, Protein Expression and Purification, 77(2): 153-158 (2011).

Ting-Kuo Huang, Michael A. Plesha, and Karen A. McDonald, “Semicontinuous Bioreactor Production of a Recombinant Human Therapeutic Protein Using a Chemically Inducible Viral Amplicon Expression System in Transgenic Plant Cell Suspension Cultures”, Biotechnology and Bioengineering, 106(3): 408-421 (2010)

Ting-Kuo Huang and Karen A. McDonald, “Bioreactor Engineering for Recombinant Protein Production in Plant Cell Suspension Cultures “, Biochemical Engineering Journal, 45: 168-184 (2009).
Michael A. Plesha, Ting-Kuo Huang, Abhaya M. Dandekar, Bryce W. Falk, and Karen A. McDonald, “Optimization of the Bioprocessing Conditions for Scale-Up of Transient Production of a Heterologous Protein in Plants Using a Chemically Inducible Viral Amplicon Expression System”, Biotechnology Progress, 25(3): 722-734 (2009).
Ting-Kuo Huang, Michael A. Plesha, Bryce W. Falk, Abhaya M. Dandekar, and Karen A. McDonald, “Bioreactor Strategies for Improving Production Yield and Functionality of a Recombinant Human Protein in Transgenic Tobacco Cell Cultures”, Biotechnology and Bioengineering, 102(2): 508-520 (2009).

Michael A. Plesha, Ting-Kuo Huang, Abhaya M. Dandekar, Bryce W. Falk and Karen A. McDonald, “High-Level Transient Production of a Heterologous Protein in Plants by Optimizing Induction of a Chemically Inducible Viral Amplicon Expression System”, Biotechnology Progress, 23(6): 1277-1285 (2007).
Elizabeth Zapalac and Karen A. McDonald, “Economic and Environmental Assessment of the Purification of Alpha-1-Antitrypsin from Transgenic Plant Cell Suspension Cultures. In Development of Sustainable Bioprocesses – Modeling and Assessment, Eds.; Heinzle, E.; Biwer, A., Wiley (2007).