{"id":17,"date":"2013-02-26T20:32:40","date_gmt":"2013-02-26T20:32:40","guid":{"rendered":"http:\/\/faculty.engineering.ucdavis.edu\/template\/?page_id=17"},"modified":"2025-06-26T00:09:35","modified_gmt":"2025-06-26T00:09:35","slug":"publications","status":"publish","type":"page","link":"https:\/\/faculty.engineering.ucdavis.edu\/passerini\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

Complete lists of published works linked below:<\/strong><\/p>\n

PubMed<\/a><\/p>\n

Google Scholar<\/a><\/p>\n

ORCID<\/a><\/p>\n

Peer-Reviewed Journal Articles:
\n<\/b><\/p>\n

Passerini AG<\/span><\/b>, Milsted A, Rittgers SE. (2003) Shear stress magnitude and directionality modulate growth factor gene expression in preconditioned vascular endothelial cells. J. Vasc. Surg<\/i>. 37: 182-190. PMID: 12514598<\/p>\n

Polacek DC*, Passerini AG<\/span><\/b>*, Shi C, Francesco NM, Manduchi E, Grant GR, Powell S, Bischof H, Winkler H, Stoeckert CJ Jr., Davies PF. (2003) Fidelity and enhanced sensitivity of differential transcription profiles following linear amplification of nanogram amounts of endothelial mRNA.\u00a0 Physiol. Genomics<\/i> 13: 147-156. PMID: 12700361 (* shared first authorship)<\/p>\n

Passerini AG<\/span><\/b>, Polacek DC, Shi C, Francesco NM, Manduchi E, Grant GR, Pritchard WF, Powell S, Chang GY, Stoeckert Jr. CJ, Davies PF. (2004) Coexisting pro-inflammatory and anti-oxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta.\u00a0 Proc. Natl. Acad. Sci. USA<\/i> 101(8): 2482-2487. PMID: 14983035<\/p>\n

Davies PF, Passerini AG<\/span><\/b>, Simmons CA. (2004) Aortic valve: turning over a new leaf(let) in endothelial phenotypic heterogeneity.\u00a0 Arterioscler. Thromb. Vasc. Biol<\/i>. 24(8): 1331-1333. PMID: 15297285<\/p>\n

Passerini AG<\/span><\/b>, Shi C, Francesco NM, Chuan P, Manduchi E, Grant GR, Stoeckert CJ Jr., Karanian JW, Wray-Cahen D, Pritchard WF, Davies PF. (2005) Regional determinants of arterial endothelial phenotype dominate the impact of gender or short-term exposure to a high-fat diet.\u00a0 Biochem. Biophys. Res. Commun<\/i>. 332: 142-148. PMID: 15896310<\/p>\n

Ting HJ, Stice JP, Schaff UY, Hui DY, Rutledge JC, Knowlton AA, Passerini AG<\/span><\/b>, Simon SI. (2007) Triglyceride-rich lipoproteins prime aortic endothelium for an enhanced inflammatory response to TNF-alpha. Circ. Res<\/i>. 100(3): 381-390. PMID: 17234968<\/p>\n

Tsou JK, Gower RM, Ting HJ, Schaff UY, Insana MF, Passerini AG<\/span><\/b>, Simon SI. (2008) Spatial regulation of inflammation by human aortic endothelial cells in a linear gradient of shear stress. Microcirculation<\/i>. 15(4): 311-323. PMID: 18464160<\/p>\n

Davies PF, Civelek M, Fang Y, Guerraty MA, Passerini AG<\/span><\/b>. (2010) Endothelial heterogeneity associated with regional athero-susceptibility and adaptation to disturbed blood flow in vivo. Special issue: Under-recognized significance of endothelial heterogeneity. Semin. Thromb. Hemost<\/i>. 36(3): 265-275. PMID: 20533180<\/p>\n

Wang YI, Schulze J, Raymond N, Tomita T, Tam K, Simon SI, Passerini AG<\/span><\/b>. (2011) Endothelial inflammation correlates with subject triglycerides and waist size following a high fat meal. Am. J. Physiol. Heart Circ. Physiol<\/i>. 300(3): H784-H791. (E-published 2010 Dec 17). PMID: 21169396<\/p>\n

DeVerse JS, Bailey KA, Jackson KN, Passerini AG<\/span><\/b>. (2012) Shear stress modulates RAGE-mediated inflammation in a model of diabetes-induced metabolic stress. Am. J. Physiol. Heart Circ. Physiol<\/i>. 302(12): H2498-H2508. (E-published 2012 Mar 30). PMID: 22467309<\/p>\n

DeVerse JS, Bailey KA, Foster GA, Mittal V, Altman SM, Simon SI, Passerini AG<\/span><\/b>. (2012) On-chip endothelial inflammatory phenotyping. J. Vis. Exp.<\/i> (65), e4169, DOI: 10.3791\/4169. PMID: 22847646<\/p>\n

Sun C, Alkhoury K, Wang YI, Foster GA, Radecke CE, Tam K, Edwards CM, Facciotti MT, Armstrong EJ, Knowlton AA, Newman JW, Passerini AG<\/span><\/b>, Simon SI. (2012) IRF-1 and miRNA126 modulate VCAM-1 expression in response to a high fat meal. Circ. Res.<\/i> 111: 1054-1064. (E-published 2012 Aug 8). PMID: 22874466<\/p>\n

Tran NK, Godwin ZR, Bockhold JC, Passerini AG<\/span><\/b>, Cheng J, Ingemason M. (2013) Clinical impact of sample interference on intensive insulin therapy in severely burned patients: a pilot study. J. Burn Care Res.<\/i> (E-published 2013 Jul 23). PMID: 23884048<\/p>\n

DeVerse JS, Sandhu AS, Mendoza N, Edwards CM, Sun C, Simon SI, Passerini AG<\/span><\/b>. (2013) Shear stress modulates VCAM-1 expression in response to TNF\u03b1 and dietary lipids via interferon regulatory factor-1 in cultured endothelium. Am. J. Physiol. Heart Circ. Physiol<\/i>. (E-published 2013 Aug 9). PMID: 23934855<\/p>\n

Wang YI, Bettaieb A, Sun C, DeVerse JS, Radecke CE, Mathew S, Edwards CM, Haj FG, Passerini AG<\/u><\/strong>, Simon SI. (2013) Triglyceride-rich lipoprotein modulates endothelial vascular cell adhesion molecule (VCAM)-1 expression via differential regulation of endoplasmic reticulum stress. PLoS One<\/em> 8(10): e78322. (E-published 2013 Oct 21). PMID: 24205197<\/p>\n

Wang H, Weihrauch D, Kersten JR, Toth JM, Passerini AG<\/u><\/strong>, Rajamani A, Schrepfer S, LaDisa JF Jr. (2015) Alagebrium inhibits neointimal hyperplasia and restores distributions of wall shear stress by reducing downstream vascular resistance in obese and diabetic rats. Am.<\/em>\u00a0J. Physiol. Heart Circ. Physiol. <\/em>309(7): H1130-H1140. (E-published 2015 Aug 7). PMID: 26254329<\/p>\n

Bailey KA, Haj FG, Simon SI, Passerini AG<\/u><\/strong>. (2017) Atherosusceptible shear stress activates endoplasmic reticulum stress to promote endothelial inflammation. Sci. Rep.<\/em> Aug 15; 7(1): 8196. doi: 10.1038\/s41598-017-08417-9. PMID: 28811527<\/p>\n

Fan X, Chen X, Feng Q, Peng K, Wu Q, Passerini AG<\/u><\/strong>, Simon SI, Sun C. (2019) Downregulation of GATA6 in mTOR-inhibited human aortic endothelial cells: effects on TNF\u03b1-induced VCAM-1 expression and monocytic cell adhesion. Am. J. Physiol. Heart Circ. Physiol. <\/em>316(2): H408-H420. (E-published 2018 Nov 21). PMID: 30462552<\/p>\n

Rajamani A, Borkowski K, Akre S, Fernandez A, Newman JW, Simon SI, Passerini AG<\/u><\/strong>. (2019) Oxylipins in triglyceride-rich lipoproteins of dyslipidemic subjects promote endothelial inflammation following a high fat meal. Sci. Rep.<\/em> Jun 17; 9(1): 8655. doi: 10.1038\/s41598-019-45005-5. PMID: 31209255<\/p>\n

Bailey KA, Moreno E, Haj FG, Simon SI, Passerini AG<\/u><\/strong>. (2019) Mechanoregulation of p38 activity enhances endoplasmic reticulum stress-mediated inflammation by arterial endothelium. FASEB J.<\/em> 33(11):12888-12899. (E-published 2019 Sep 7). doi: 10.1096\/fj.201900236R. PMID: 31499005<\/p>\n

Rand AA, Rajamani A, Kodani SD, Harris TR, Schlatt L, Barnych B, Passerini AG<\/u><\/strong>, Hammock BD. (2019) Epoxyeicosatrienoic acid (EET)-stimulated angiogenesis is mediated by epoxy hydroxyeicosatrienoic acids (EHETs) formed from COX-2. J.<\/em> Lipid Res.<\/em> 60(12):1996-2005. (E-published 2019 Oct 22). doi: 10.1194\/jlr.M094219. PMID: 31641036<\/p>\n

Peng K, Fan X, Li Q, Wang Y, Chen X, Xiao P, Passerini AG<\/u><\/strong>, Simon SI, Sun C. (2020) IRF-1 mediates the suppressive effects of mTOR inhibition on arterial endothelium. J.<\/em> Mol. Cell. Cardiol.<\/em> 140(2020): 30\u201341. (E-published 2020 Feb 19). doi: 10.1016\/j.yjmcc.2020.02.006. PMID: 32087218<\/p>\n

Hernandez AA, Foster GA, Soderberg SR, Fernandez A, Reynolds MB, Orser MK, Bailey KA, Rogers JH, Singh GD, Wu H, Passerini AG<\/u><\/strong>, Simon SI. (2020) An allosteric shift in CD11c affinity activates a proatherogenic state in arrested intermediate monocytes. J.<\/em> Immunol.<\/em> Nov 15; 205(10): 2806-2820. (E-published 2020 Oct 14). doi: 10.4049\/jimmunol.2000485. PMID: 33055281<\/p>\n

Hu C, Peng K, Wu Q, Wang Y, Fan X, Zhang DM, Passerini AG<\/u><\/strong>, Sun C. (2021) HDAC1 and 2 regulate endothelial VCAM-1 expression and atherogenesis by suppressing methylation of the GATA6 promoter. Theranostics.<\/em> Mar 20; 11(11): 5605-5619. doi: 10.7150\/thno.55878. eCollection 2021. PMID: 33859766<\/p>\n

Chen X, Wang Y, Li Q, Fan X, Hu C, Su YQ, Zhang DM, Yang Q, Passerini AG<\/u><\/strong>, Sun C. (2021) mTOR Inhibition Promotes Pneumonitis Through Inducing Endothelial Contraction and Hyperpermeability. Am.<\/em> J. Respir. Cell. Mol. Biol.<\/em> Dec; 65(6): 646-657. doi: 10.1165\/rcmb.2020-0390OC. Epub ahead of print. PMID: 34251297<\/p>\n

Wang Y, Li Q, Zhang Z, Peng K, Zhang DM, Yang Q, Passerini AG<\/u><\/strong>, Simon SI, Sun C. (2022) mTOR contributes to endothelium-dependent vasorelaxation by promoting eNOS expression and preventing eNOS uncoupling. Commun. <\/em> Biol.<\/em> Jul 22; 5(1): 726. doi: 10.1038\/s42003-022-03653-w. PMID: 35869262<\/p>\n

Fan X, Li Q, Wang Y, Zhang DM, Zhou J, Chen Q, Sheng L, Passerini AG<\/u><\/strong>, Sun C. (2023) Non-canonical NF-\u03baB contributes to endothelial pyroptosis and atherogenesis dependent on IRF-1. Transl. Res.<\/em> May; 255: 1-13. doi:10.1016\/j.trsl.2022.11.001. Epub 2022 Nov 13. PMID: 36384204<\/p>\n

Li T, Conroy KL, Kim AM, Halmai J, Gao K, Moreno E, Wang A, Passerini AG<\/u><\/strong>, Nolta JA, Zhou P. (2023) Role of MEF2C in the Endothelial Cells Derived from Human Induced Pluripotent Stem Cells. Stem Cells.<\/em> Apr 25; 41(4): 341-353. doi:10.1093\/stmcls\/sxad005. PMID: 36639926<\/p>\n

Sun C, Sun H, Wei J, Fan X, Simon SI, Passerini AG<\/u><\/strong>. (2024) IRF-1 Regulates Mitochondrial Respiration and Intrinsic Apoptosis Under Metabolic Stress through ATP Synthase Ancillary Factor TMEM70. Inflammation<\/em>. Epub 2024 Dec 6. doi: 10.1007\/s10753-024-02209-w. PMID: 39641858<\/p>\n

Book Chapters:<\/b><\/p>\n

Passerini AG<\/span><\/b>. (2010) Genomic approaches to endothelial cell phenotyping. In Hsiai TK, Blackman B, Jo H, (Eds.), Hemodynamics and Mechanobiology of Endothelium<\/span> (pp. 179-211). World Scientific Publishing Co.<\/p>\n","protected":false},"excerpt":{"rendered":"

Complete lists of published works linked below: PubMed Google Scholar ORCID Peer-Reviewed Journal Articles: Passerini AG, Milsted A, Rittgers SE. (2003) Shear stress magnitude and directionality modulate growth factor gene expression in preconditioned vascular endothelial cells. J. Vasc. Surg. 37: 182-190. PMID: 12514598 Polacek DC*, Passerini AG*, Shi C, Francesco \u2026 Continue reading → <\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":{"inline_featured_image":false,"ngg_post_thumbnail":0,"footnotes":""},"class_list":["post-17","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/faculty.engineering.ucdavis.edu\/passerini\/wp-json\/wp\/v2\/pages\/17","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/faculty.engineering.ucdavis.edu\/passerini\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/faculty.engineering.ucdavis.edu\/passerini\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/faculty.engineering.ucdavis.edu\/passerini\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/faculty.engineering.ucdavis.edu\/passerini\/wp-json\/wp\/v2\/comments?post=17"}],"version-history":[{"count":16,"href":"https:\/\/faculty.engineering.ucdavis.edu\/passerini\/wp-json\/wp\/v2\/pages\/17\/revisions"}],"predecessor-version":[{"id":276,"href":"https:\/\/faculty.engineering.ucdavis.edu\/passerini\/wp-json\/wp\/v2\/pages\/17\/revisions\/276"}],"wp:attachment":[{"href":"https:\/\/faculty.engineering.ucdavis.edu\/passerini\/wp-json\/wp\/v2\/media?parent=17"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}