Huang Y, Harris BS, Minami SA, Jung S, Shah PS, Nandi S, McDonald K, Faller R. SARS-Cov-2 Spike binding to ACE2 is stronger and longer ranged with glycans. [bioRxiv pre-print]. 2021 July. doi:10.1101/2021.07.15.452507
Petit MJ, Kenaston MK, Nagainis AN, Shah PS (corresponding author). Nuclear dengue virus NS5 antagonized expression of PAF1-dependent immune response genes. [bioRxiv preprint]. 2021 April 6. doi:10.1101/2021.04.06.438514
Minami SA, Shah PS (corresponding author). Transient light-activated gene expression in Chinese hamster ovary cells. BMC Biotechnology. 2021 Feb 4. doi:10.1186/s12896-021-00670-1
Leon K, Flynn R, Khalid MM, Fontaine KA, Nguyen T, Kumar GR, Simoneau CR, Tomar S, Jimenez-Morales D, Dunlap M, Kaye J, Shah PS, Finkbeiner S, Krogan NJ, Bertozzi C, Carette JE, Ott M. Zika virus infection prevents host mRNA nuclear export by disrupting UPF1 function. [bioRxiv preprint] 2020 Dec 7. doi:10/1101/2020/12.03.410837.
Link N, Chung H, Jolly A, Withers M, Tepe B, Arenkiel BR, Shah PS, Krogan NJ, Aydin H, Geckinli BB, Tos T, Isikay S, Tuysuz B, Mochida GH, Thomas AX, Clark RD, Mirzaa GM, Lupski JR, Bellen HJ. Mutations in ANKLE2, a ZIKA Virus Target, Disrupt an Asymmetric Cell Division Pathway in Drosophila Neuroblasts to Cause Microcephaly. Developmental Cell. 2019 Dec 16. doi.org/10.1016/j.devcel.2019.10.009. PMID 31735666
Li M, Johnson JR, Truong B, Kim G, Weinbren N, Dittmar M, Shah PS, Von Dollen J, Newton BW, Jang GM, Krogan NJ, Cherry S, Ramage H. Identification of antiviral roles for the exon-junction complex and nonsense-mediated decay in flaviviral infection. Nature Microbiology. 2019 Jun 4. doi.org/10.1038/s41564-019-0375-z. PMID 30833725
Petit MJ, Shah PS. Mapping Arbovirus-Vector Interactions Using Systems Biology Approaches. Frontiers in Cellular and Infection Microbiology. 2019 Jan 7. doi.org/10.3389/fcimb.2018.00440
Shah PS, Link N, Jang GM, Sharp PP, Zhu T, Swaney DL, Johnson JR, Von Dollen J, Ramage HR, Satkamp L, Newton B, Hüttenhain R, Petit MJ, Baum T, Everitt A, Laufman O, Tassetto M, Shales M, Stevenson E, Iglesias GN, Shokat L, Tripathi S, Balasubramaniam V, Webb LG, Aguirre S, Willsey AJ, Garcia-Sastre A, Pollard KS, Cherry S, Gamarnik AV, Marazzi I, Taunton J, Fernandez-Sesma A, Bellen HJ, Andino R, Krogan NJ. Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis. Cell. 2018 Dec 13. doi: 10.1016/j.cell.2018.11.028 PMID 30550790.
Fontaine KA, Leon KE, Khalid MM, Tomar S, Jimenez-Morales D, Dunlap M, Kaye JA, Shah PS, Finkbeiner S, Krogan NJ, Ott M.The Cellular NMD Pathway Restricts Zika Virus Infection and Is Targeted by the Viral Capsid Protein. MBio. 2018 Nov 6. doi: 10.1128/mBio.02126-18. PMID 29191913.
Eckhardt M, Zhang W, Gross AM, Von Dollen J, Johnson JR, Franks-Skiba KE, Swaney DL, Johnson TL, Jang GM, Shah PS, Brand TM, Archambault J, Kreisberg JF, Grandis JR, Ideker T, Krogan NJ. Multiple Routes to Oncogenesis Are Promoted by the Human Papillomavirus-Host Protein Network. Cancer Discov. 2018 Sep 12. doi: 10.1158/2159-8290.CD-17-1018. PMID 30209081.
De Maio FA, Risso G, Iglesias NG, Shah P, Pozzi B, Gebhard LG, Mammi P, Mancini E1 Yanovsky MJ, Andino R, Krogan N, Srebrow A,Gamarnik AV. The Dengue Virus NS5 Protein Intrudes in the Cellular Spliceosome and Modulates Splicing. PLoS Pathogens. 2016 Aug 30;12(8):e1005841 PMID 27575636.
Heaton NS, Moshinka N, Fenouil R, Gardner TJ, Aguirre S, Shah PS, Zhao N, Manganaro L, Hultquist J, Noel J, Sachs D, Hamilton J, Leon PE, Chawdury A, Tripathy S, Melegari C, Campisi L, Hai R, Metreveli G, Gamarnik AV, Garcia-Sastre A, Greenbaum B, Simo V, Fernandez-Sesma A, Krogan NJ, Mulder LCF, van Bakel H, Tortorella D, Taunton J, Palese P, Marazzi I. Limiting influenza virus, HIV and dengue virus infection by targeting viral proteostasis. Immunity. 2016 Feb 16;44(2):438 PMID 26789921.
Shah PS, Wojcechowskyj JA, Eckhardt M, Krogan NJ. Comparative mapping of host-pathogen protein-protein interactions. Current Opinions in Microbiology. 2015 Aug 10;27:62-68 PMID 26275922
Ramage HR, Kumar GR, Verschueren E, Johnson JR, Von Dollen J, Johnson T, Newton B, Shah P, Horner J, Krogan NJ, Ott M. A combined proteomics/genomics approach links hepatitis C virus infection with nonsense-mediated mRNA decay. Molecular Cell. 2015 Jan 22;57(2):329-40. PMID 25616068
Miller-Jensen K, Skupsky R, Shah PS, Arkin AP, Schaffer DV. Genetic Selection for Context-Dependent Stochastic Phenotypes: Sp1 and TATA Mutations Increase Phenotypic Noise in HIV-1 Gene Expression. PLoS Computational Biology. 2013 July (7) e1003135; PMID 23874178.
Ashton RS, Conway A, Pangarkar C, Bergen J, Lim KI, Shah P, Bissell M, Schaffer DV. Astrocytes regulate adult hippocampal neurogenesis through ephrin-B signaling. Nature Neuroscience. 2012 Oct;15(10):1399-406. PMID 22983209.
Shah PS, Pham NP, Schaffer DV. HIV Develops Indirect Cross-resistance to Combinatorial RNAi Targeting Two Distinct and Spatially Distant Sites. Molecular Therapy. 2012 Apr;20(4):840-8. PMID 22294151.
Shah PS, Schaffer DV. Antiviral RNAi: Translating Science Towards Therapeutic Success. Pharmaceutical Research. 2011 Dec;28(12):2966-82. PMID 21826573.
Aviran S, Shah PS, Schaffer DV, Arkin AP. Computational Models of HIV-1 Resistance to Gene Therapy Elucidate Therapy Design Principles. PLoS Computational Biology. 2010 Aug 12;6(8) e1000883. PMID 20711350.
Shah PS, Schaffer DV. Gene therapy takes a cue from HAART: Combinatorial antiviral therapeutics reach the clinic. Science Translational Medicine. 2010 Jun:2(36). PMID 2055021.
Burnett JC, Miller-Jensen K, Shah PS, Arkin AP, Schaffer DV. Control of stochastic gene expression by host factors at the HIV promoter. PLoS Pathogens. 2009 Jan;5(1) e1000260. PMID 19132086.
Shah PS (co-first author), Leonard JN (co-first author), Burnett JC, Schaffer DV. HIV evades RNA interference directed at TAR by an indirect compensatory mechanism. Cell Host and Microbe. 2008 Nov 13;4(5):484-94.* *Featured open-access article. PMID 18996348.
Liu, S, Pereira NA, Teo JJ, Miller P, Shah P, Song Z. Mitochondrially targeted Bcl-2 and Bcl-X(L) chimeras elicit different apoptotic responses. Molecules and Cells, 2007 Dec 31;24(3):378-87 PMID 18182854.
Vahedi-Faridi A, Brault PA, Shah P, Kim YW, Dunham WR, Funk MO Jr. Interaction between non-heme iron of lipoxygenases and cumene hydroperoxide: basis for enzyme activation, inactivation, and inhibition. Journal of the American Chemical Society. 2004 Feb 25;126(7):2006-15. PMID 14971933.
Brault PA, Kariapper MS, Pham CV, Flowers RA 2nd, Gunning WT, Shah P, Funk MO Jr. Protein micelles from lipoxygenase 3. Biomacromolecules. 2002 Jul-Aug;3(4):649-54. PMID 12099806.
