Associate Professor Sharon Aviran

Biomedical Engineering
451 E. Health Sciences Dr.
GBSF, Room 2319
University of California
Davis, CA 95616

Email: saviran at ucdavis.edu

Website: Aviran Lab

Phone: (530) 752-6978

Research

Computational RNA Biology and Medicine

We work at the interface of data science and RNA biology/medicine, developing probabilistic models and machine learning algorithms to study RNA structure and function and applying these algorithms in large-scale genomic data analyses. One area of interest is transcriptome-wide analysis of post-transcriptional dynamics via integration of data from diverse high-throughput assays to infer sequence-structure-function relationships. RNA functions we study include RNA-protein interactions, gene expression, and stability or half-life (in vitro and in vivo). We are also interested in modeling the folding of RNA molecules using both biophysical models and high-throughput experiments, with the overarching goal of advancing the structure-driven discovery and engineering of novel RNAs for therapeutic and biotechnology applications.