Publications

Peer-Reviewed Journal Articles:

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Passerini AG, Milsted A, Rittgers SE. (2003) Shear stress magnitude and directionality modulate growth factor gene expression in preconditioned vascular endothelial cells. J. Vasc. Surg. 37: 182-190. PMID: 12514598

Polacek DC*, Passerini AG*, Shi C, Francesco NM, Manduchi E, Grant GR, Powell S, Bischof H, Winkler H, Stoeckert CJ Jr., Davies PF. (2003) Fidelity and enhanced sensitivity of differential transcription profiles following linear amplification of nanogram amounts of endothelial mRNA.  Physiol. Genomics 13: 147-156. PMID: 12700361 (* shared first authorship)

Passerini AG, Polacek DC, Shi C, Francesco NM, Manduchi E, Grant GR, Pritchard WF, Powell S, Chang GY, Stoeckert Jr. CJ, Davies PF. (2004) Coexisting pro-inflammatory and anti-oxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta.  Proc. Natl. Acad. Sci. USA 101(8): 2482-2487. PMID: 14983035

Davies PF, Passerini AG, Simmons CA. (2004) Aortic valve: turning over a new leaf(let) in endothelial phenotypic heterogeneity.  Arterioscler. Thromb. Vasc. Biol. 24(8): 1331-1333. PMID: 15297285

Passerini AG, Shi C, Francesco NM, Chuan P, Manduchi E, Grant GR, Stoeckert CJ Jr., Karanian JW, Wray-Cahen D, Pritchard WF, Davies PF. (2005) Regional determinants of arterial endothelial phenotype dominate the impact of gender or short-term exposure to a high-fat diet.  Biochem. Biophys. Res. Commun. 332: 142-148. PMID: 15896310

Ting HJ, Stice JP, Schaff UY, Hui DY, Rutledge JC, Knowlton AA, Passerini AG, Simon SI. (2007) Triglyceride-rich lipoproteins prime aortic endothelium for an enhanced inflammatory response to TNF-alpha. Circ. Res. 100(3): 381-390. PMID: 17234968

Tsou JK, Gower RM, Ting HJ, Schaff UY, Insana MF, Passerini AG, Simon SI. (2008) Spatial regulation of inflammation by human aortic endothelial cells in a linear gradient of shear stress. Microcirculation. 15(4): 311-323. PMID: 18464160

Davies PF, Civelek M, Fang Y, Guerraty MA, Passerini AG. (2010) Endothelial heterogeneity associated with regional athero-susceptibility and adaptation to disturbed blood flow in vivo. Special issue: Under-recognized significance of endothelial heterogeneity. Semin. Thromb. Hemost. 36(3): 265-275. PMID: 20533180

Wang YI, Schulze J, Raymond N, Tomita T, Tam K, Simon SI, Passerini AG. (2011) Endothelial inflammation correlates with subject triglycerides and waist size following a high fat meal. Am. J. Physiol. Heart Circ. Physiol. 300(3): H784-H791. (E-published 2010 Dec 17). PMID: 21169396

DeVerse JS, Bailey KA, Jackson KN, Passerini AG. (2012) Shear stress modulates RAGE-mediated inflammation in a model of diabetes-induced metabolic stress. Am. J. Physiol. Heart Circ. Physiol. 302(12): H2498-H2508. (E-published 2012 Mar 30). PMID: 22467309

DeVerse JS, Bailey KA, Foster GA, Mittal V, Altman SM, Simon SI, Passerini AG. (2012) On-chip endothelial inflammatory phenotyping. J. Vis. Exp. (65), e4169, DOI: 10.3791/4169. PMID: 22847646

Sun C, Alkhoury K, Wang YI, Foster GA, Radecke CE, Tam K, Edwards CM, Facciotti MT, Armstrong EJ, Knowlton AA, Newman JW, Passerini AG, Simon SI. (2012) IRF-1 and miRNA126 modulate VCAM-1 expression in response to a high fat meal. Circ. Res. 111: 1054-1064. (E-published 2012 Aug 8). PMID: 22874466

Tran NK, Godwin ZR, Bockhold JC, Passerini AG, Cheng J, Ingemason M. (2013) Clinical impact of sample interference on intensive insulin therapy in severely burned patients: a pilot study. J. Burn Care Res. (E-published 2013 Jul 23). PMID: 23884048

DeVerse JS, Sandhu AS, Mendoza N, Edwards CM, Sun C, Simon SI, Passerini AG. (2013) Shear stress modulates VCAM-1 expression in response to TNFα and dietary lipids via interferon regulatory factor-1 in cultured endothelium. Am. J. Physiol. Heart Circ. Physiol. (E-published 2013 Aug 9). PMID: 23934855

Wang YI, Bettaieb A, Sun C, DeVerse JS, Radecke CE, Mathew S, Edwards CM, Haj FG, Passerini AG, Simon SI. (2013) Triglyceride-rich lipoprotein modulates endothelial vascular cell adhesion molecule (VCAM)-1 expression via differential regulation of endoplasmic reticulum stress. PLoS One 8(10): e78322. (E-published 2013 Oct 21). PMID: 24205197

Wang H, Weihrauch D, Kersten JR, Toth JM, Passerini AG, Rajamani A, Schrepfer S, LaDisa JF Jr. (2015) Alagebrium inhibits neointimal hyperplasia and restores distributions of wall shear stress by reducing downstream vascular resistance in obese and diabetic rats. J. Physiol. Heart Circ. Physiol. 309(7): H1130-H1140. (E-published 2015 Aug 7). PMID: 26254329

Bailey KA, Haj FG, Simon SI, Passerini AG. (2017) Atherosusceptible shear stress activates endoplasmic reticulum stress to promote endothelial inflammation. Sci Rep. Aug 15; 7(1): 8196. doi: 10.1038/s41598-017-08417-9. PMID: 28811527

Fan X, Chen X, Feng Q, Peng K, Wu Q, Passerini AG, Simon SI, Sun C. (2019) Downregulation of GATA6 in mTOR-inhibited human aortic endothelial cells: effects on TNFα-induced VCAM-1 expression and monocytic cell adhesion. J. Physiol. Heart Circ. Physiol. 316(2): H408-H420. (E-published 2018 Nov 21). PMID: 30462552

Book Chapters:

Passerini AG. (2010) Genomic approaches to endothelial cell phenotyping. In Hsiai TK, Blackman B, Jo H, (Eds.), Hemodynamics and Mechanobiology of Endothelium (pp. 179-211). World Scientific Publishing Co.

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