Research Interests

The broad objective of my research is to explore microscale multiphase flows in biology, tissue engineering, and materials. In particular, my lab develops novel ex vivo microfluidic approaches and combine in vivo multiphoton microscopy to investigate the contributions of cerebral microcirculation, neurovascular coupling, and cerebrospinal fluids to neurodegenerative diseases and aging. We also explore stem cell biology and long-term 3D cell culture systems to develop Organ-on-a-Chip devices including intestine-on-chip and brain-on-chip. We further combine interfacial dynamics and fluid dynamics in microfluidics with material science and engineering to investigate the synthesis of advanced functional materials for biomedical therapeutics and applications in energy technology. The ultimate goals of my research are to advance our fundamental understanding of multiphase fluid dynamics in these fields and provide ground-breaking technologies, devices, and materials.

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